A research group has demonstrated that overexpression of Cdc10-dependent transcript 1 (CDT1), a key regulator of DNA ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication ...

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both sides of ...

A new study demonstrates that replicative senescence depends upon ATM kinase, and that high oxygen generates a hyperactive ...

A free account provides you access to a limited number of free articles each month, plus newsletters, job postings, salary data, and exclusive store discounts.

Scientists comment on a UK Health Security Agency (UKHSA) announcement that a new mpox strain has been identified in England. Dr Jonas Albarnaz, Institute Fellow, Capripoxvirus Biology, Pirbright ...

For the first time since HIV was identified, early human trials are starting to show what long‑imagined “drug‑free control” ...

Harvard scientists have defined the exact DNA cross-link created by colibactin, a gut microbial toxin associated with ...

DNA can sustain serious injuries called double strand breaks, in which both strands of the helix snap. These breaks are among ...

An international research team has identified a human protein, ANKLE1, as the first DNA-cutting enzyme (nuclease) in mammals ...

High-resolution imaging has revealed the internal layout of chromatin condensates, showing how DNA fibers fold and interact ...