From retired Third Circuit Judge Thomas Vanaskie (who had also served on the Middle District of Pennsylvania), and who ...
Cedars-Sinai scientists have created a new experimental drug called TY1 that helps the body repair damaged DNA and restore ...
After two decades in the making, scientists have cracked the code on a drug that can repair DNA, setting the scene for a new ...
When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key ...
The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break-when both sides of the DNA helix are cut at once.
A specific form of epigenetic aging, ACCA drift, accumulates in intestinal stem cells, silencing key genes through hypermethylation. Driven by age-related inflammation, weakened Wnt signaling and ...
"Genes affected by these variations are linked to critical biological processes and may help explain individual differences in health and disease." The study also found distinct patterns in STR ...
The Downtown Neighborhood Association of Elgin is being evicted from its city-owned office space after the nonprofit notified city officials it wouldn’t be signing a new contract in which the terms ...
The bowhead whale’s remarkable lifespan and low cancer risk stem from a finely tuned DNA repair system driven by a unique protein, CIRBP. Scientists found that this mechanism not only preserves the ...
One of the biggest challenges in cancer treatment is chemoresistance: Tumors that initially respond well to chemotherapy become resistant over time. When that happens, treatment options are often ...
Using comparative molecular biology with human cGAS – which actually inhibits DNA repair – the scientists found that the naked mole-rat's enzyme has four key changes that facilitate the important work ...
Naked mole-rats are well known for both their wrinkly appearance and for their unexpectedly long lives. The source of this extended lifespan has been under scrutiny for decades. While many rodents are ...